Neutral amino acid transport systems of tissue culture cells.
نویسندگان
چکیده
منابع مشابه
Neutral amino acid transport systems of tissue culture cells.
We have studied the interactions among a varied group of neutral amino acids for uptake into two different animal tissue culture cell lines. 3T3 mouse cells and Chinese hamster ovary cells were used in these studies. The results showed that the affinities of the amino acids clustered into two groups, one including amino acids such as glycine, alanine, and alpha-aminoisobutyric acid and the othe...
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The neutral amino acid transport systems A, ASC, and L have been characterized in the Chinese hamster ovary cell. System A, defined by its sodium ion dependency and inhibition by 2-methylaminoisobutyric acid, was found to be extremely sensitive to the pH of the external medium and to increase in response to starvation for amino acids. System ASC, identified by its sodium ion dependency and into...
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Amino acid movement across cell membranes is mediated by a variety of transport systems. These pathways have been extensively studied and characterized in a large array of cell types and include both Na+-dependent and Naf-independent carriers. In addition, recent work suggests that channels may also play a role in amino acid transport. The objective of the present paper is to review current kno...
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II1. Regu la t ion of t r anspor t ac t iv i ty by amino acid avai lab i l i ty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269 A, Regula t ion of System A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269 B. Regula t ion of System L . . . . . . . . . . . . . . ....
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The roles of the cell membrane as both a permeability barrier to foreign substances and as a selective filter which admits nutrient molecules have been recognized as fundamentally important to animal physiology since the first decade of this century. It was not until the 1950's, however, that microbiologists recognized that bacteria possess membrane transport systems, distinct from their metabo...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1977
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)40511-4